Table of Contents

Unraveling the crucial roles of Meis1 in leukemogenesis and normal hematopoiesis

• Bob Argiropoulos,
• Eric Yung,
• and R. Keith Humphries

A missed exit: Reelin sets in motion Dab1 polyubiquitination to put the break on neuronal migration

• Géraldine Kerjan
• and Joseph G. Gleeson

Autophagy: process and function

• Noboru Mizushima

Riboswitch-dependent gene regulation and its evolution in the plant kingdom

• Samuel Bocobza,
• Avital Adato,
• Tali Mandel,
• Michal Shapira,
• Evgeny Nudler,
• and Asaph Aharoni

Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb–MuvB/dREAM complex in proliferating cells

• Daphne Georlette,
• Soyeon Ahn,
• David M. MacAlpine,
• Evelyn Cheung,
• Peter W. Lewis,
• Eileen L. Beall,
• Stephen P. Bell,
• Terry Speed,
• J. Robert Manak,
• and Michael R. Botchan

Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2–7 loading

• Shuyan Chen,
• Milan A. de Vries,
• and Stephen P. Bell

Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication

• Priya Aggarwal,
• Matthew D. Lessie,
• Douglas I. Lin,
• Laura Pontano,
• Andrew B. Gladden,
• Beth Nuskey,
• Ami Goradia,
• Mariusz A. Wasik,
• Andres J.P. Klein-Szanto,
• Anil K. Rustgi,
• Craig H. Bassing,
• and J. Alan Diehl

β-Catenin induces immortalization of melanocytes by suppressing p16^INK4a expression and cooperates with N-Ras in melanoma development

• Véronique Delmas,
• Friedrich Beermann,
• Silvia Martinozzi,
• Suzanne Carreira,
• Julien Ackermann,
• Mayuko Kumasaka,
• Laurence Denat,
• Jane Goodall,
• Flavie Luciani,
• Amaya Viros,
• Nese Demirkan,
• Boris C. Bastian,
• Colin R. Goding,
• and Lionel Larue

Transcription of histone gene cluster by differential core-promoter factors

• Yoh Isogai,
• Sündüz Keles,
• Matthias Prestel,
• Andreas Hochheimer,
• and Robert Tjian

Pin1 modulates RNA polymerase II activity during the transcription cycle

• Yu-Xin Xu
• and James L. Manley

Global analysis of alternative splicing differences between humans and chimpanzees

• John A. Calarco,
• Yi Xing,
• Mario Cáceres,
• Joseph P. Calarco,
• Xinshu Xiao,
• Qun Pan,
• Christopher Lee,
• Todd M. Preuss,
• and Benjamin J. Blencowe

Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants

• Andrew V. Samuelson,
• Christopher E. Carr,
• and Gary Ruvkun

The neurohormone orexin stimulates hypoxia-inducible factor-1 activity

• Devanjan Sikder
• and Thomas Kodadek

Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells

• Susana M. Garcia,
• M. Olivia Casanueva,
• M. Catarina Silva,
• Margarida D. Amaral,
• and Richard I. Morimoto

Erratum